## Overview

Teaching:60 min

Exercises:120 minQuestions

What is power

Why is it important: issues with low statistical power

Some tools for power for neuroimaging

Objectives

After this lesson, you should understand what is Power, and the issues of low statistical power

First, we will be doing some work on this notebook:

How to work with the notebook ? There are two cases.

- You do not really know python, and how to install the jupyter notebook. You can still read the notebook, skipping the code sections. The notebook will introduce some definitions, and then play with different settings. But the true benefit comes if you can install the jupyter project see here and actually play with the code, for instance changing the sample size or effect size to understand better what power is.
- Download the notebook, and try to understand the concepts and the code. If the code is unclear, please make an issue on the repronim github site

Exercise: visit this site and set your test to be one tailed at the false positive risk of 0.05. Say a typical effect size in fMRI corresponds to a Cohen’s d of 0.5. What is the sample size that you find ? Now, relate to what we are doing in fMRI. What is the problem ? can you use this online tool to get the number of subjects for your experiment ? if yes, give a typical example, if not, explain the problem.

Then, on this one:

Last, you’ll need to go through :

## Key Points

The lack of power is much more problematic that it seems at first sight. - It would usually lead to wasted resources - If an under powered study yields some significant effects, these are likely to be overestimated - If an under powered study yields some significant effects, these are less likely to replicate